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KMID : 0616620030090020155
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Journal of Soonchunhyang Medical College
2003 Volume.9 No. 2 p.155 ~ p.163
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A Clinical Study of Tsutsugamushi Fever in Children during 1997-2003 in the Northwestern Choongnam Province
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Kwon Ki-Beom
Park Joon-Soo
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Abstract
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Purpose: Tsutsugamushi fever has been reported in Korean children. However there are not any reports regarding children of the Northwestern Choongnam province. Hence we are reporting clinical features of the Tsutsugamushi disease in chidren of these area.
Methods: We reviewed clinically or serologically confirmed 11 Children of Tsutsugamushi fever from Cheonan and Choongchung Nam Province, who were admitted to Soonchunhyang University Cheonan Hospital from October 1997 through October 2003. We investigated the age, sex ratio, clinical manifestations, laboratory findings and response to therapy.
Results: The mean age of patients was 6.5 years, ranging from 2 to 14 years. 7 cases(63.6%) were bovs and 4 cases(36.4%) were girls. The mean duration of the treatment was 6.8 days. The most common symptoms were fever in all cases and cough in 2 cases (18.1%). Frequent signs were skin rash in all cases, eschar in 9 cases (81.8), regional lymphadenopathy in 3 cases (27.2%). The main locations of the eschars were neck in 3 cases(33.3%), and chest, thigh, penis, occipital, back, ear in each 1. Laboratory findings included leukopenia in 4 cases(36.3%), lejkocytosis in 3 cases(27.2%), anemia in 2, ESR elevation in 5, and positive CRP in all cases, SGOT elevation in 9 cases, SGPT elevation in 8 cases, positive passive hem agglutination test in 7 cases (63.6%). Clinical improvement was noticed in all cases after treatment with chloramphenicol, tetracycline, doxycycline, or roxythromycin. The mean duration for defervescence after treatment was 1.4 days. There were not complications or recurrence in any case.
Conclusions: Tsutsugamushi fever have appeared in children of Cheonan and Choongnam Province. We should be aware of clinical manifestation such as fever, skin rash, eschar, and lymphadenopathy during the period of October and November in order to diagnose the Tsutsugamushi fever properly.
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KEYWORD
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Tsutsugamushi fever, Children, Cheoan, Choongnam Province
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